New PDF release: Bacteriophages: Biology and Applications

By Alexander Sulakvelidze, Elizabeth Kutter

ISBN-10: 0849313368

ISBN-13: 9780849313363

According to the emergence of pathogenic micro organism that can not be taken care of with present antibiotics, many researchers are revisiting using bacteriophages, or phages, to struggle multidrug-resistant micro organism. Bacteriophages: Biology and functions presents unprecedented, finished details on bacteriophages and their functions, similar to phage treatment. It bargains thoughts, media, and method interested by separating and dealing with healing phages. images, line drawings, and electron micrographs of phages also are integrated. With its extensive procedure, this publication is an invaluable reference for microbiologists, hematologists, and infectious disorder researchers.

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Extra resources for Bacteriophages: Biology and Applications

Example text

In the immediate postwar period, a French biologist, Raymond Latarjet, came to the United States as part of a government program to reinvigorate and modernize French science. , the number of “hits” needed to completely inactivate an infected bacterium so that it could not produce a plaque). Latarjet was introduced to Luria soon after his arrival in America, and because Luria was also involved in phage radiobiology, they began a famous collaboration that resulted in a paradigmatic experiment that came to be called the Luria-Latarjet Bacteriophage Research: Early History 17 Experiment (Luria and Laterjet, 1947).

Muller contributed significantly to the effort to define the understanding of the nature of the gene as the critical problem in biology (Keller, 1990). This group discussed ways in which physics might be applied to biology to understand the nature of the gene, and in 1935 this threesome published a famous paper on the nature of gene structure and mutation (Timofeev-Ressovsky, Zimmer, and Delbrück, 1935). Their goal was, in the words of Gunther Stent (1963, p. H. Morgan, the head of the Biology Division at Caltech, invited Delbrück to visit Caltech as a Rockefeller Foundation Fellow.

Sometimes the infecting phage initiates a lytic cycle, resulting in lysis of the cell and release of new phage, as previously shown. The infecting phage may alternatively initiate a lysogenic cycle; instead of replicating, the phage genome assumes a quiescent state called a prophage, often integrated into the host genome but sometimes maintained as a plasmid. , capable of producing lysis) because one of these prophages occasionally comes out of its quiescent condition and enters the lytic cycle.

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Bacteriophages: Biology and Applications by Alexander Sulakvelidze, Elizabeth Kutter

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