Beyond Neurotransmission: Neuromodulation and Its Importance - download pdf or read online

By Paul S. Katz

ISBN-10: 0198524242

ISBN-13: 9780198524243

ISBN-10: 0585483965

ISBN-13: 9780585483962

This ebook presents the principles for realizing the mobile and molecular foundation for neuromodulatory results. It illustrates key examples of the jobs performed by way of neuromodulation in sensory processing, neuromuscular transmission, new release of motor behaviors, and studying. The publication additionally underscores the significance of knowledge processing by means of the anxious method in destiny reports. For neurobiology scholars and researchers, the ebook summarizes an unlimited volume of analysis within the context of ways those mobile mechanisms are utilized in structures of neurons. through spanning the degrees of study from sub-cellular mechanisms via mobile homes and neuronal platforms to behaviour, the e-book offers a framework for figuring out this speedily advancing box. The language is on the market to a person with a simple realizing of neurobiology, yet covers subject matters extensive for these accustomed to neuromodulation and data processing.

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Extra resources for Beyond Neurotransmission: Neuromodulation and Its Importance for Information Processing

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The temporal encoding window is equivalent to the time between spikes in a burst and requires only the first two action potentials to encode the sinusoid period. decoding which is significantly shorter than that of individual bursts of action potentials. By narrowing the duration of this 'encoding window' differently patterned bursts of action potentials can convey additional information even if their mean firing rate is identical. A definition of temporal encoding has been proposed to distinguish it from window-averaged rate encoding (Theunissen and Miller 1995).

This type of coding applies not only to sensory systems but can be applied to motor systems as well; particular neurons 'code' for movement of particular muscles simply because those are the muscles with which they synapse. Although the identity of the axon provides some gross identification about the information that it is conveying, further detail, such as the quality of the stimulus, its temporal dynamics, or its intensity, must be coded in the sequence of action potentials carried by that axon.

1994). Metabotropic glutamate receptors: synaptic transmission, modulation, and plasticity. Neuron, 13, 1031-7. Neer, E. J. (1997). Intracellular signaling: turning down G-protein signals. Current Biology, 7, R31-3. Newman, E. A. and Zahs, K. R. (1997). Calcium waves in retinal glial cells. Science, 275, 844-7. Nusbaum, M. P. (1994). Presynaptic control of neurons in pattern-generating networks. Current Opinion in Neurobiology, 4, 909-14. Otmakhova, N. A. and Lisman, J. E. (1996). D1/D5 dopamine receptor activation increases the magnitude of early long-term potentiation at CA1 hippocampal synapses.

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Beyond Neurotransmission: Neuromodulation and Its Importance for Information Processing by Paul S. Katz

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