New PDF release: Breeding for Disease Resistance in Farm Animals

By Stephen C. Bishop, Roger F. E. Axford, Frank W. Nicholas, John B. Owen

ISBN-10: 1845935551

ISBN-13: 9781845935559

This re-creation offers an up to date assessment of the rules of animal breeding for complex health and wellbeing and ailment resistance. Authored through specialists, it makes use of examples protecting many illnesses of value to farm animals creation throughout all significant farm animals species. themes comprise concepts and methods, viruses, Transmissible Spongiform Encephalopathies (TSEs), micro organism, parasites, vectors, and broader healthiness concerns noticeable in construction structures, together with metabolic ailments.

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Additional resources for Breeding for Disease Resistance in Farm Animals

Example text

Pathogen type Microparasites Most viral and bacterial parasites, and many protozoan and fungal parasites, may be classified as microparasites. Microparasites may be thought of as those that have direct reproduction, usually at very high rates, within the host (Anderson and May, 1992). They tend to be characterized by small size, a short generation time which is often just a fraction of that of their host and a short duration of infection. Hosts that recover from infection usually acquire immunity against reinfection for some time, and often for life.

2008) Targeting chemokine receptors in HIV: A status report. Annual Review of Pharmacology and Toxicology 48, 425–461. , Kronenberg, M. and Cheroutre, H. (2001) T cell responses modulated through interaction between CD8 and the nonclassical MHC class I molecule, TL. Science 294, 1936–1939. , Morgan, K. and Malo, D. (2003) Allelic variation in TLR4 is linked to susceptibility to Salmonella enterica serovar The Immune System Typhimurium infection in chickens. Infection and Immunity 71, 1116–1124.

We are only now beginning to understand the complexity of CD4+ T cell subsets and the role they play in controlling adaptive immune responses. Selection for resistance at the level of an adaptive response is possible, but potentially problematic. It is unlikely to give resistance to even closely related pathogens and, depending on the gene(s) involved, it is possible that it might lead to increased susceptibility to some other pathogens. The innate immune response, by contrast, is focused on responses to wide classes of pathogens.

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Breeding for Disease Resistance in Farm Animals by Stephen C. Bishop, Roger F. E. Axford, Frank W. Nicholas, John B. Owen

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