By Paul Vanhoutte
Heart problems continues to be a massive reason for demise and incapacity in constructed international locations and, more and more so, within the constructing world. Presented during this quantity of Advances in Pharmacology are the most promising percentages for treating huge numbers of people bothered with those conditionsThis quantity includes updated experiences of crucial rising cardiovascular remedies written by way of global leaders within the box.
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Additional info for Cardiovascular Pharmacology: Endothelial Control
2001). Enhanced endothelin-1-induced contractions in mesenteric arteries from rats with congestive heart failure: Role of ET(B) receptors. European Journal of Heart Failure, 3, 293–299. Bialecki, R. , Izzo, N. J. , & Colucci, W. S. (1989). Endothelin-1 increases intracellular calcium mobilization but not calcium uptake in rabbit vascular smooth muscle cells. Biochemical and Biophysical Research Communications, 164, 474–479. , & D’Orleans-Juste, P. (2000). Presence of functional endothelin-1 receptors in nuclear membranes of human aortic vascular smooth muscle cells.
Journal of Cardiovascular Pharmacology, 36, 344–350. Watts, S. W. (2010). Endothelin receptors: What’s new and what do we need to know? American Journal of Physiology—Regulatory, Integrative and Comparative Physiology, 298, R254–R260. Wisler, J. , DeWire, S. , Whalen, E. , Violin, J. , Drake, M. , Shenoy, S. , & Lefkowitz, R. J. (2007). A unique mechanism of beta-blocker action: Carvedilol stimulates beta-arrestin signaling. Proceedings of the National Academy of Sciences of the United States of America, 104, 16657–16662.
1991). Endothelin induces a nonselective cation current in vascular smooth muscle cells. Circulation Research, 69, 447–454. , Bogoyevitch, M. , Anderson, M. , & Sugden, P. H. (1994). Differential activation of protein kinase C isoforms by endothelin-1 and phenylephrine and subsequent stimulation of p42 and p44 mitogen-activated protein kinases in ventricular myocytes cultured from neonatal rat hearts. The Journal of Biological Chemistry, 269, 32848–32857. , Garcia-Villalon, A. , & Dieguez, G. (2005).
Cardiovascular Pharmacology: Endothelial Control by Paul Vanhoutte