By S. M. Hitchen, J. R. Dean (auth.), John R. Dean (eds.)
The endured look for speedy, effective and least expensive technique of analytical dimension has brought supercritical fluids into the sphere of analytical chemistry. components are universal: supercritical fluid chroma tography and supercritical fluid extraction. either search to use the original houses of a gasoline at temperatures and pressures above the serious element. the commonest supercritical fluid is carbon dioxide, hired due to its low serious temperature (31 °C), inertness, purity, non-toxicity and cheapness. substitute supercritical fluids also are used and sometimes along side modifiers. The mixed gas-like mass move and liquid-like solvating features were used for enhanced chroma tographic separation and speedier pattern practise. Supercritical fluid chromatography (SFC) is complementary to gasoline chro matography ( GC) and excessive functionality liquid chromatography (HPLC), supplying larger potency than HPLC, including the power to examine thermally labile and excessive molecular weight analytes. either packed and open tubular columns might be hired, delivering the potential to examine a variety of pattern varieties. furthermore, flame ionization detection can be utilized, hence offering 'universal' detection.