By Harald Klaus Theml, Heinz Diem, Torsten Haferlach
A Flexibook for either the professional and non-specialist, the new e-book bargains obtainable info on hematology in a succinct layout. as well as offering simple technique, the publication makes use of greater than 260 colour illustrations to element the main updated medical approaches. various tables and circulate charts are integrated to help in differential prognosis, making this a priceless didactic reference for nurses, training physicians and citizens getting ready for board examinations.
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Extra resources for Color atlas of hematology: practical microscopic and clinical diagnosis
4. After careful consideration of the results obtained so far and the patient's clinical record, the last step is the analysis of the cell composition of the bone marrow. Quite often, suspected diagnoses are confirmed through humoral tests such as electrophoresis, or through cytochemical tests such as alkaline phosphatase, myeloperoxidase, nonspecific esterase, esterase, or iron tests. Bone marrow analysis is indicated when clinical findings and blood analysis leave doubts in the diagnostic assessment, for example in cases of: ➤ Leukocytopenia ➤ Thrombocytopenia ➤ Undefined anemia ➤ Tricytopenia, or ➤ Monoclonal hypergammaglobulinemia A bone marrow analysis may be indicated in order to evaluate the spreading of a lymphadenoma or tumor, unless the bloodstream already shows the presence of pathological cells.
A left shift indicates a greater than normal proportion of immature cells and a right shift a greater than normal proportion of mature cells (Table 4). , the nucleus shows the structure of a myelocyte while the cytoplasm is still strongly basophilic. In malignancies, the picture is dominated by blasts, which may often be difficult to identify with any certainty. A left shift is observed in all reactive processes and at the start of neoplastic transformation (smoldering anemia, refractory anemia with excess blasts [RAEB]).
Significance of the Automated Blood Count The qualitative and quantitative blood count techniques described here may seem somewhat archaic given the now almost ubiquitous automated cell counters; they are merely intended to show the possibilities always ready to be called on in terms of individual analyses carried out by small, dedicated laboratories. The automated cell count has certainly rationalized blood cell counting. Depending on the diagnostic problem and the quality control system of the individual laboratory, automated counting can even reduce data ranges compared with “manual” counts.
Color atlas of hematology: practical microscopic and clinical diagnosis by Harald Klaus Theml, Heinz Diem, Torsten Haferlach