Dan Longo's Harrison's Hematology and Oncology, 2e PDF

By Dan Longo

ISBN-10: 0071814906

ISBN-13: 9780071814904

Hematology and Oncology – as merely Harrison’s can conceal it

A Doody's center name for 2015.

Featuring an outstanding compilation of chapters on hematology and oncology that seem in Harrison’s rules of inner drugs, Eighteenth Edition, this concise, full-color medical better half provides the newest wisdom within the box sponsored via the medical rigor and authority that experience outlined Harrison’s. you will discover content material from popular editors and individuals in a carry-anywhere presentation that's perfect for the study room, health facility, ward, or exam/certification preparation.


  • Organized into twelve sections: The mobile foundation of Hematopoiesis; Cardinal Manifestations of Hematologic ailments; Anemias, Myeloproliferative issues; Hematologic Malignancies; issues of Hemostasis; Biology of melanoma; ideas of melanoma Prevention and remedy; Neoplastic problems; Endocrine Neoplasia; distant results of melanoma; and Oncologic Emergencies and past due results issues
  • Each bankruptcy contents suitable details at the genetics, mobile biology, pathophysiology, and remedy of particular ailment entities
  • Chapters on hematopoiesis, melanoma phone biology, and melanoma prevention replicate the swiftly starting to be physique of data in those areas
  • Integration of pathophysiology with scientific management
  • 153 high-yield questions and solutions drawn from Harrison’s ideas of inner medication Self-Assessment and Board overview, 18e
  • Content updates and new advancements because the e-book of Harrison’s rules of inner drugs, 18e
  • 55 chapters written by means of physicians who're famous specialists within the box of hematology and oncology
  • Helpful appendix of laboratory values of scientific importance

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Extra resources for Harrison's Hematology and Oncology, 2e

Sample text

Abdominal vessel thromboses are particularly common. Neurologic symptoms such as vertigo, tinnitus, headache, and visual disturbances may occur. Hypertension is often present. Patients with polycythemia vera may have aquagenic pruritus and symptoms related to hepatosplenomegaly. Patients may have easy bruising, epistaxis, or bleeding from the gastrointestinal tract. Peptic ulcer disease is common. Patients with hypoxemia may develop cyanosis on minimal exertion or have headache, impaired mental acuity, and fatigue.

Maturation disorders are ­identified from the discrepancy between the M/E ratio and the reticulocyte production index discussed later). Either the marrow smear or biopsy can be stained for the presence of iron stores or iron in developing red cells. The storage iron is in the form of ferritin or hemosiderin. On carefully prepared bone marrow smears, small ferritin granules can normally be seen under oil immersion in 20–40% of developing erythroblasts. Such cells are called sideroblasts. Other Laboratory Measurements Additional laboratory tests may be of value in confirming specific diagnoses.

However, it is the most common symptom in hereditary hemorrhagic telangiectasia and in boys with VWD. Clues that epistaxis is a symptom of an underlying bleeding disorder include lack of ­seasonal variation and bleeding that requires medical evaluation or treatment, including cauterization. Bleeding with eruption of primary teeth is seen in children with more severe bleeding disorders, such as moderate and severe hemophilia. It is uncommon in children with mild bleeding disorders. Patients with disorders of primary hemostasis (platelet adhesion) may have increased bleeding after dental cleanings and other procedures that involve gum manipulation.

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Harrison's Hematology and Oncology, 2e by Dan Longo

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