By Alice D. Ma, Harold R. Roberts, Miguel A. Escobar
Chapter I normal evaluate (pages 1–27):
Chapter II Hemophilia with Inhibitors (pages 29–50):
Chapter III Hemophilic therapy for systems (pages 51–84):
Chapter IV therapy for different stipulations (pages 85–96):
Chapter V different concerns in Hemophilia Care (pages 97–104):
Chapter VI Compound Diagnoses (pages 105–117):
Chapter I administration in the course of approaches (pages 119–133):
Chapter II infrequent types of von Willebrand ailment (pages 135–143):
Chapter III different Bleeding problems (pages 145–168):
Chapter IV obtained Bleeding issues (pages 169–196):
Chapter V Thrombotic problems (pages 197–218):
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Extra resources for Hemophilia and Hemostasis: A Case-Based Approach to Management
He began the FIX desensitization protocol modified from Dioun et al. (1998) and Chuansumrit et al. 1). The cumulative dose for each day was 100 units/kg of recombinant FIX. 1 Desensitization protocol. 2 Coagulation studies before and after ITI. 4 100 units/kg/day On the first day of desensitization, the patient experienced a rash with urticaria near the infusion site. The symptoms resolved quickly after administration of diphenhydramine and hydrocortisone. The subsequent days of infusion were well tolerated.
Reference DiMichele DM (2011) Immune tolerance induction in haemophilia: evidence and the way forward. J Thromb Haemost 9(Suppl 1): 216–225. C ASE STU DY 6 Severe Hemophilia B with High Response Inhibitor and Anaphylactic Reaction to Factor IX Jenny M. Splawn,1 Benjamin Carcamo,2 and Miguel A. Escobar3 1 Providence Memorial Hospital, El Paso, TX, USA 2 Pediatric Hematology Oncology, Providence Memorial Hospital, and Texas Tech University School of Medicine, El Paso, TX, USA 3 Division of Hematology, University of Texas Health Science Center at Houston and Gulf States Hemophilia and Thrombophilia Center, Houston, TX, USA The patient was diagnosed at 6 months of age with severe factor IX deficiency after presenting with several large subcutaneous, soft tissue, and intramuscular hematomas.
Retina 30(9): 1386–1389. C ASE STU DY 1 1 Endoscopy/Colonoscopy and Hemophilia Alice D. Ma Division of Hematology/Oncology, University of North Carolina, Chapel Hill, NC, USA A 51-year-old man with mild hemophilia A, baseline factor level of 7% is scheduled for routine screening colonoscopy. He does not treat himself with factor at home, and his response to DDAVP shows that his FVIII level rises to 15% at 1 h after desmopressin. Q What is the recommendation for factor replacement around the time of his procedure?
Hemophilia and Hemostasis: A Case-Based Approach to Management by Alice D. Ma, Harold R. Roberts, Miguel A. Escobar