By Robert Marcus, John W. Sweetenham, Michael E. Williams
Significant advances have happened in virtually each point of the analysis and remedy of lymphoma in recent times. Our knowing of the molecular biology and genetics of the ailment has elevated exponentially, and important advancements in imaging of this malignancy have ended in previous and extra actual prognosis. while, advances in healing immunology have ended in the improvement of numerous new treatments. This landmark new textual content describes those advances in one concise quantity, putting them within the context of day-by-day medical perform. Introductory chapters assessment epidemiology, prognostic components, imaging and healing immunology. those are by way of chapters on every one lymphoma subtype, dealing comprehensively with all points of the analysis and therapy of the ailment. hugely illustrated in complete color all through and written and edited through the prime specialists within the box, this publication presents the entire info had to diagnose and deal with those complicated issues.
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Additional resources for Lymphoma: Pathology, Diagnosis and Treatment
Variable frequencies of MALT lymphoma-associated genetic aberrations in lymphomas of different sites. Leukemia 18 (2004), 1722–1726. 3 IMAGING Ashley S. Shaw and Adrian K. Dixon INTRODUCTION STAGING TECHNIQUES The radiologist plays a key role in the management of patients with lymphoma at several stages, from initial diagnosis through to the evaluation of response to treatment. The possible diagnosis of lymphoma is often raised first by the imaging department. The alert radiologist who identifies an abnormal mediastinum on a chest radiograph may consider lymphoma in the diagnosis, and this may prompt further investigations.
And Gascoyne, R. D. Molecular pathogenesis of mucosa-associated lymphoid tissue lymphoma. J. Clin. Oncol. 23 (2005), 6370–6378. 3. Molecular subgroups of diffuse large B-cell lymphoma (DLBCL). , Campo, E. and Rosenwald, A. Pathogenesis of mantle-cell lymphoma: all oncogenic roads 17 Part I Lymphoma Overview lead to dysregulation of cell cycle and DNA damage response pathways. J. Clin. Oncol. 23 (2005), 6364–6369. Hamblin, T. , Oscier, D. G. and Stevenson, F. K. Unmutated Ig V (H) genes are associated with Hodgkin’s lymphoma.
J. Clin. Oncol. 23 (2005), 6351–6357. , Diehl, V. , Chan, W. C. et al. The use of molecular profiling to predict survival after chemotherapy for diffuse large-B-cell lymphoma. N. Engl. J. Med. 346 (2002), 1937–1947. , Wiestner, A. et al. The proliferation gene expression signature is a quantitative integrator of oncogenic events that predicts survival in mantle cell lymphoma. Cancer Cell 3 (2003), 185–197. , Mullauer, L. et al. Variable frequencies of MALT lymphoma-associated genetic aberrations in lymphomas of different sites.
Lymphoma: Pathology, Diagnosis and Treatment by Robert Marcus, John W. Sweetenham, Michael E. Williams