By Philip Lanzkowsky
Totally up to date to mirror glossy pondering and protocols, the handbook of Pediatric Hematology and Oncology offers concise info wanted for the daily administration of kids with pediatric hematologic and oncologic illnesses. The transparent variety permits readers to make a correct prognosis and allows him/her to regard sufferers no matter if they've got now not had broad prior hematologic or oncologic event. Pertinent advances in molecular genetics, cytogenetics, immunology, transplantation and biochemistry are the results of forty years of useful adventure via the writer within the administration of sufferers and comprises quite a few individuals who've had large scientific event. * positive aspects a variety of tables, movement diagrams, protocols, and algorithms for speedy entry of crucial medical details worthwhile for the analysis and administration of those ailments in youngsters* Designed as a concise, effortless to take advantage of consultant for clinical scholars, citizens, fellows, pediatric hematologists/oncologists, pediatric nurses and nurse practitioners* a lot of the sensible info contained during this guide isn't present in common textbooks* effortless sort with none redundant phrases or references
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Extra resources for Manual of Pediatric Hematology and Oncology, Fourth Edition
Continues) 5. Severe illness with birth of infant with hydrops fetalis, stillbirth, or death in utero and delivery of a macerated fetus. 6. Late hyporegenerative anemia with absent reticulocytes. This occurs occasionally during the second to the fifth week and is due to a diminished population of erythroid progenitors (serum concentration of erythropoietin is low and the marrow concentrations of BFU-E and CFU-E are not elevated). Laboratory Findings 1. Serologic abnormalities (incompatibility between blood group of infant and mother; direct Coombs’ test positive in infant; mother’s serum has the presence of immune antibodies detected by the indirect Coombs’ test) 2.
In unusual or obscure cases of hypochromic anemia, it is necessary to do additional Iron-Deficiency Anemia 41 Table 3-8. Diagnostic Tests for Iron-Deficiency Anemia 1. Blood smear a. 0 pg (3) MCHC less than 30% b. 5% 2. Free erythrocyte protoporphyrin: elevated 3. Serum ferritin: decreased 4. Serum iron and iron binding capacity a. Decreased serum iron b. Increased iron-binding capacity c. Decreased iron saturation (16% or less) 5. Therapeutic responses to oral iron a. Reticulocytosis with peak 5–10 days after institution of therapy b.
Hepatobiliary system: hematobilia 3. Lung: pulmonary hemosiderosis, Goodpasture syndrome, defective iron mobilization with IgA deficiency 4. Nose: recurrent epistaxis 5. Uterus: menstrual loss 6. Heart: intracardiac myxomata, valvular prostheses or patches 7. , paroxysmal nocturnal hemoglobinuria, paroxysmal cold hemoglobinuria, march hemoglobinuria) 8. Extracorporeal: hemodialysis, trauma IV. Impaired absorption Malabsorption syndrome, celiac disease, severe prolonged diarrhea, postgastrectomy, inflammatory bowel disease, Helicobacter pylori infection associated chronic gastritis.
Manual of Pediatric Hematology and Oncology, Fourth Edition by Philip Lanzkowsky