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Ontological framework for enterprise-wide integrated decision-making at operational level. Computers & Chemical Engineering 42, 217–234 (2012) 10. : Past, Present, and Future of Industrial Agent Applications. IEEE Transactions on Industrial Informatics 9(4), 2360–2372 (2013) 11. : Advanced process automation using automation agents. In: Proceedings of the 5th International Conference on Automation, Robotics and Applications, pp. 34–39 (2011) A Survey on Standards and Ontologies for Process Automation 31 12.

O. Silisteanu the last stage, final products are packed and transported to the clients in shielded containers. A typical radiopharmaceutical product workflow is presented in Fig. 1. The preparation of radiopharmaceuticals requires a safe, clean and aseptic workplace. Special environment conditions must be fulfilled continuously during the manufacturing process. These conditions could be divided in two main categories: radioprotection safety conditions (radioactivity doses, pressure cascades and air change cycles) and environment manufacturing conditions (temperature, humidity and pressure, number of particles) as defined by GMP1, guide or recommended by IAEA2 in their technical reports [1].

Other requirement of these control systems is ensuring collaboration and integration of heterogeneous, autonomous and distributed manufacturing subsystems to take advantages of local facilities. The combination of Holonic and Multi-Agent System (HMAS) and Service-Oriented Architecture (SOA) techniques is effective to design this Reconfigurable and Distributed Manufacturing Control System (RDMCS). However, there are few methods based on formalisms which ensure a systematic workflow to implement a RDMCS considering since its abstraction phase.

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Special-Catalogue of light- and narrow gauge-locomotives, lokomotives for contractors and industrial purposes, fireless locomotives by Krauss und Comp.

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